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People

Eriksson Anders

Position: Postdoctoral Research Associate

Telephone: +44 (0)1223 767129
Email: aje44@cam.ac.uk

Eriksson Anders

Research

I have a broad interest in understanding how different types of population dynamics and structure, combined with the effects of selection, mutation and recombination, shape the patterns of genetic variation observed in animal and human populations. My present research is focused on modeling how the early history of anatomically modern human migration and settlement has shaped present-day genetic variation. Using spatially explicit models of movement of individuals between populations, in combination with realistic models of microsatellite evolution, we attempt to reconstruct the tempo and mode of human expansion out of Africa by fitting the model to the large databases of global genetic variation that has become available over the last decade. In our present model the world is partitioned into hexagonal cells of approximately equal size, each containing a population (see figure below for an illustration). Population growth, migration between connected populations, and genetics are modelled using a graph representation of each cell. The historic population growth and migration are determined by local climate and topography, which have been reconstructed using global models of past climate.

Model
Illustration of the spatially explicit model. Black dots show the locations of the cells.

Publications

2014

44)     Clemente, FJ, Cardona, A, Inchley, CE, Peter, BM, Jacobs, G, Pagani, L, Lawson, DJ, Antão, T, Vicente, M, Mitt, M, DeGiorgio, M, Faltyskova, Z, Xue, Y, Ayub, Q, Szpak, M, Mägi, R, Eriksson, A, Manica, A, Raghavan, M, Rasmussen, M, Rasmussen, S, Willerslev, E, Vidal-Puig, A, Tyler-Smith, C, Villems, R, Nielsen, R, Metspalu, M, Malyarchuk, B, Derenko, M, Kivisild, T. 2014. A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations. The American Journal of Human Genetics 95: 584–589. [PDF]

43)     Rieux, A, Eriksson, A, Li, M, Sobkowiak, B, Weinert, LA, Warmuth, V, Ruiz-Linares, A, Manica, A, Balloux, F. 2014. Improved Calibration of the Human Mitochondrial Clock Using Ancient Genomes. Molecular Biology and Evolution 31: 2780–2792. [PDF]

42)     Rasmussen, M, Anzick, SL, Waters, MR, Skoglund, P, DeGiorgio, M, Stafford Jr, TW, Rasmussen, S, Moltke, I, Albrechtsen, A, Doyle, SM, Poznik, GD, Gudmundsdottir, V, Yadav, R, Malaspinas, A-S, V, SSW, Allentoft, ME, Cornejo, OE, Tambets, K, Eriksson, A, Heintzman, PD, Karmin, M, Korneliussen, TS, Meltzer, DJ, Pierre, TL, Stenderup, J, Saag, L, Warmuth, VM, Lopes, MC, Malhi, RS, Brunak, S, Sicheritz-Ponten, T, Barnes, I, Collins, M, Orlando, L, Balloux, F, Manica, A, Gupta, R, Metspalu, M, Bustamante, CD, Jakobsson, M, Nielsen, R, Willerslev, E. 2014. The genome of a Late Pleistocene human from a Clovis burial site in western Montana. Nature 506: 225–229. [PDF] [Media]

41)     Eriksson, A, Elías-Wolff, F, Mehlig, B, Manica, A. 2014. The emergence of the rescue effect from explicit within- and between-patch dynamics in a metapopulation. Proceedings of the Royal Society B: Biological Sciences 281: 20133127. [PDF]

40)     Eriksson, A, Manica, A. 2014. The Doubly Conditioned Frequency Spectrum Does Not Distinguish between Ancient Population Structure and Hybridization. Molecular Biology and Evolution 31: 1618–1621. [PDF]

2013

39)     Warmuth, VM, Campana, MG, Eriksson, A, Bower, M, Barker, G, Manica, A. 2013. Ancient trade routes shaped the genetic structure of horses in eastern Eurasia. Mol Ecol 22: 5340–5351. [PDF]

38)     Eriksson, A, Elías-Wolff, F, Mehlig, B. 2013. Metapopulation dynamics on the brink of extinction. Theoretical Population Biology 83: 101–122. [PDF]

37)     Warmuth, V, Manica, A, Eriksson, A, Bower, MA, Barker, G. 2013. Autosomal genetic diversity in non-breed horses from eastern Eurasia provides insights into historical population movements. Animal Genetics 44: 53–61. [PDF]

2012

36)     Eriksson, A, Manica, A. 2012. Effect of ancient population structure on the degree of polymorphism shared between modern human populations and ancient hominins. Proceedings of the National Academy of Sciences 109: 13956–13960. [PDF] [Media]

35)     Eriksson, A, Betti, L, Friend, AD, Lycett, SJ, Singarayer, JS, Cramon-Taubadel, N von, Valdes, PJ, Balloux, F, Manica, A. 2012. Late Pleistocene climate change and the global expansion of anatomically modern humans. Proceedings of the National Academy of Sciences 109: 16089–16094. [PDF] [Media]

34)     Warmuth, V, Eriksson, A, Bower, MA, Barker, G, Barrett, E, Hanks, BK, Li, S, Lomitashvili, D, Ochir-Goryaeva, M, Sizonov, GV, Soyono, V, Manica, A. 2012. Reconstructing the Origin and Spread of Horse Domestication in the Eurasian Steppe. Proceedings of the National Academy of Sciences 109: 8202–8206. [PDF] [Media]

33)     Schaper, E, Eriksson, A, Rafajlovic, M, Sagitov, S, Mehlig, B. 2012. Linkage Disequilibrium Under Recurrent Bottlenecks. Genetics 190: 217–229. [PDF]

32)     Harding, KC, Begon, M, Eriksson, A, Wennberg, B. 2012. Increased migration in host–pathogen metapopulations can cause host extinction. Journal of Theoretical Biology 298: 1–7. [PDF] [Suppl. Mat.]

2011

31)     Eriksson, A, Manica, A. 2011. Detecting and Removing Ascertainment Bias in Microsatellites from the HGDP-CEPH Panel. G3: Genes, Genomes, Genetics 1: 479–488. [PDF]

30)     McNamara, JM, Trimmer, PC, Eriksson, A, Marshall, JAR, Houston, AI. 2011. Environmental variability can select for optimism or pessimism. Ecology Letters 14: 58–62. [PDF]

29)     Rasmussen, M, Guo, X, Wang, Y, Lohmueller, KE, Rasmussen, S, Albrechtsen, A, Skotte, L, Lindgreen, S, Metspalu, M, Jombart, T, Kivisild, T, Zhai, W, Eriksson, A, Manica, A, Orlando, L, De La Vega, FM, Tridico, S, Metspalu, E, Nielsen, K, Ávila-Arcos, MC, Moreno-Mayar, JV, Muller, C, Dortch, J, Gilbert, MTP, Lund, O, Wesolowska, A, Karmin, M, Weinert, LA, Wang, B, Li, J, Tai, S, Xiao, F, Hanihara, T, Van Driem, G, Jha, AR, Ricaut, F-X, De Knijff, P, Migliano, AB, Gallego Romero, I, Kristiansen, K, Lambert, DM, Brunak, S, Forster, P, Brinkmann, B, Nehlich, O, Bunce, M, Richards, M, Gupta, R, Bustamante, CD, Krogh, A, Foley, RA, Lahr, MM, Balloux, F, Sicheritz-Pontén, T, Villems, R, Nielsen, R, Wang, J, Willerslev, E. 2011. An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia. Science 334: 94–98. [PDF] [Suppl. Mat.] [Media]

28)     Svensson, C, Eriksson, A, Harkonen, T, Harding, K. 2011. Detecting Density Dependence in Recovering Seal Populations. AMBIO: A Journal of the Human Environment 40: 52–59. [PDF]

27)     Warmuth, V, Eriksson, A, Bower, MA, Canon, J, Cothran, G, Distl, O, Glowatzki-Mullis, M-L, Hunt, H, Luis, C, Oom, M do M, Tupac Yupanqui, I, Zabek, T, Manica, A. 2011. European Domestic Horses Originated in Two Holocene Refugia. Plos One 6: e18194. [PDF] [Suppl. Mat.]

2010

26)     Eriksson, A, Mehlig, B, Rafajlovic, M, Sagitov, S. 2010. The Total Branch Length of Sample Genealogies in Populations of Variable Size. Genetics 186: 601–611. [PDF]

25)     Eriksson, A, Mehlig, B, Panova, M, Andre, C, Johannesson, K. 2010. Multiple paternity: determining the minimum number of sires of a large brood. Molecular Ecology Resources 10: 282–291. [PDF]

24)     Eriksson, A, Nilsson Jacobi, M, Nyström, J, Tunstrøm, K. 2010. Determining Interaction Rules in Animal Swarms. Behavioral Ecology 21: 1106–1111. [PDF]

23)     Panova, M, Boström, J, Hofving, T, Areskoug, T, Eriksson, A, Mehlig, B, Mäkinen, T, André, C, Johannesson, K. 2010. Extreme Female Promiscuity in a Non-Social Invertebrate Species. PLoS ONE 5: e9640. [PDF]

22)      Tanabe, K, Mita, T, Jombart, T, Eriksson, A, Horibe, S, Palacpac, N, Ranford-Cartwright, L, Sawai, H, Sakihama, N, Ohmae, H, Nakamura, M, Ferreira, MU, Escalante, AA, Prugnolle, F, Bjorkman, A, Farnert, A, Kaneko, A, Horii, T, Manica, A, Kishino, H, Balloux, F. 2010. Plasmodium falciparum Accompanied the Human Expansion out of Africa. Current Biology 20: 1283–1289. [PDF] [Suppl. Mat.] [Media]

2009

21)     Eriksson, A, Nilsson Jacobi, M, Nyström, J, Tunstrøm, K. 2009. Bottom-up derivation of an effective thermostat for united atoms simulations of water. The Journal of Chemical Physics 130: 164509–164509–6. [PDF]

20)     Eriksson, A, Nilsson Jacobi, M, Nyström, J, Tunstrøm, K. 2009. A method for estimating the interactions in dissipative particle dynamics from particle trajectories. Journal of Physics: Condensed Matter 21: 095401. [PDF]

19)     Eriksson, A, Nilsson Jacobi, M, Nyström, J, Tunstrøm, K. 2009. On the microscopic foundation of dissipative particle dynamics. EPL (Europhysics Letters) 86: 44001. [PDF]

18)     Eriksson, A, Mahjani, B, Mehlig, B. 2009. Sequential Markov coalescent algorithms for population models with demographic structure. Theoretical Population Biology 76: 84–91. [PDF]

17)     Füchslin, RM, Fellermann, H, Eriksson, A, Ziock, H-J. 2009. Coarse graining and scaling in dissipative particle dynamics. The Journal of Chemical Physics 130: 214102–214102–8. [PDF]

2008

16)     Eriksson, A, Nilsson Jacobi, M, Nyström, J, Tunstrøm, K. 2008. Effective thermostat induced by coarse graining of simple point charge water. The Journal of Chemical Physics 129: 024106–024106–8. [PDF]

15)     Eriksson, A, Nilsson Jacobi, M, Nyström, J, Tunstrøm, K. 2008. Using force covariance to derive effective stochastic interactions in dissipative particle dynamics. Phys. Rev. E 77: 016707. [PDF]

14)     Eriksson, A, Fernström, P, Mehlig, B, Sagitov, S. 2008. An Accurate Model for Genetic Hitchhiking. Genetics 178: 439–451. [PDF]

2006

13)     Eriksson, A, Görnerup, O, Nilsson Jacobi, M, Steen Rasmussen. 2006. Quasi-Species and Aggregate Dynamics. In: Rocha, LM, Yaeger, LS, Bedau, MA, Floreano, D, Goldstone, RL, Vespignani, A, editors. Artificial Life X: Proceedings of the Tenth International Conference on the Simulation and Synthesis of Living Systems. MIT Press. [PDF]

12)     Lindgren, K, Eriksson, A. 2006. A simple model of cognitive processing in repeated games. Saïd Business School, University of Oxford. [PDF]

11)     Eriksson, A, Lindgren, K. 2006. The effect of finite population size on the evolutionary dynamics in multi-person Prisoner’s Dilemma. Saïd Business School, University of Oxford. [PDF]

2005

10)     Eriksson, A, Mehlig, B. 2005. On the Effect of Fluctuating Recombination Rates on the Decorrelation of Gene Histories in the Human Genome. Genetics 169: 1175–1178. [PDF]

9)     Eriksson, A, Lindgren, K. 2005. Cooperation driven by mutations in multi-person Prisoner’s Dilemma. Journal of Theoretical Biology 232: 399–409. [PDF]

2004

8)     Lindgren, K, Eriksson, A, Eriksson, K-E. 2004. Flows of information in spatially extended chemical dynamics. In: Pollack, J, editor. Artificial life IX: proceedings of the Ninth International Conference on the Simulation and Synthesis of Artificial Life. MIT Press. [PDF]

7)     Stäring, J, Eriksson, A, Mehlig, B. 2004. Fluctuations of the Shannon capacity in a Rayleigh model of wireless communication. Physica status solidi (b) 241: 2136–2138. [PDF]

6)     Eriksson, A, Lindgren, K, Lundh, T. 2004. War of attrition with implicit time cost. Journal of Theoretical Biology 230: 319–332. [PDF]

5)     Eriksson, A, Mehlig, B. 2004. Gene-history correlation and population structure. Physical Biology 1: 220–228. [PDF]

2003

4)     Eriksson, A, Lindgren, K. 2003. Cooperation in an Unpredictable Environment. In: Standish, RK, Bedau, MA, Abbass, HA, editors. Artificial life eight. MIT Press. [PDF]

2002

3)     Eriksson, A, Haubold, B, Mehlig, B. 2002. Statistics of selectively neutral genetic variation. Phys. Rev. E 65: 040901. [PDF]

2001

2)     Eriksson, A, Lindgren, K. 2001. Evolution of strategies in repeated stochastic games with full information of the payoff matrix. In: Spector, L, editor. GECCO-2001 : proceedings of the Genetic and Evolutionary Computation Conference : a joint meeting of the sixth annual Genetic Programming Conference (GP-2001) and the tenth International Conference on Genetic Algorithms (ICGA-2001) : July 7-11, 2001, San Francisco, California. San Francisco: Morgan Kaufmann Publishers. [PDF]

1999

1)     Nordin, P, Eriksson, A, Nordahl, M. 1999. Genetic Reasoning: Evolutionary Induction of Mathematical Proofs. In: Poli, R, Nordin, P, Langdon, W, Fogarty, T, editors. Genetic Programming Lecture Notes in Computer Science. Springer Berlin / Heidelberg, p 651–651. [PDF]